Synonyms: 3,7-Dihydroxycholan-24-oic acid; 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid; Ursodiol
Molecular Formula: C24H40O4
Molecular Weight: 392.58
CAS Number: 128-13-2
EINECS: 204-879-3
Ursodeoxycholic acid can be chemically synthesized. Ursodeoxycholic acid reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery. The drug is very expensive, however, and if the patient stops taking it, the gallstones tend to recur if the condition that gave rise to their formation does not change. For these reasons, Ursodeoxycholic acid has not supplanted surgical treatment by cholecystectomy.
UDCA is used to treat primary biliary cirrhosis. In children, its use is not licensed, as its safety and effectiveness are not established. Ursodeoxycholic acid reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting liver cells.
Specification
Test Items | Specifications |
Appearance | White or off-white crystalline powder |
Identification | Accord with the test |
Assay | 98.5-101.5% |
Particle size | 98% pass 40 mesh |
Specific rotation | +57o to +62o |
Melting point | 200-205o |
Loss on drying | 1.0% Max |
Residue on ignition | 0.2% Max |
Heavy metals | 10ppm Max |
Packing: 25KG net fiber drum.
Storage: Stored in a dry and cool place, keep away from strong light and heat.
Shelf life: Two years when stored properly in a well-closed container.
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