1077-28-7 Alpha Lipoic Acid

Name: alpha  Lipoic acid

Synonyms:  (R)-(+)-1,2-Dithiolane-3-pentanoic acid

Molecular Formula:  C₈H₁₄O₂S₂

Molecular Weight:  206.33

CAS Number:  1200-22-2

 Alpha Lipoic acid is a disulfide compound found naturally in mitochondria as the coenzyme for pyruvate dehydrogenase and a-ketoglutarate dehydrogenase. Alpha lipoic acid (ALA) is a unique, vitamin-like antioxidant which exists in two forms, R-alpha-lipoic acid and S-alpha-lipoic acid. These two forms contain the same number and composition of atoms but have different arrangements of the atoms in their respective molecules. Natural lipoic acid is R Alpha lipoic acid. Synthetic lipoic acid contains a 50/50 mixture of the two forms. Studies with the mixture demonstrated beneficial effects in treating a number of diseases and conditions. More recent research has shown that the R Alpha Lipoic acid alone is far more effective than S Alpha Lipoic acid or the mixture. Recently, pure R Alpha Lipoic acid has become available as a nutritional supplement.

R Alpha Lipoic acid is regarded by many as the supreme antioxidant. R-Lipoic acid is unique in that it functions as both a fat and water-soluble antioxidant that can easily cross cell membranes. Thus, it can confer free radical protection to both interior and exterior cellular structures. In summary, R Lipoic Acid acts as a potent anti-oxidant on its own, serves to regenerate other anti-oxidants like vitamin E, Vitamin C and glutathione, and increases the production of glutathione. As a nutritional supplement, doses of 50 to 100 mg. per day are generally recommended. As a Therapeutic agent, higher doses may be used.

Specification

Package:  In 5Kg or 25KG net each, cardboard drums with inner plastic bags.

Storage:   Stored in a dry and cool place at temperature below 30°C, keep away from strong light and heat.

Shelf life: Two years when stored properly in a well-closed container.